Esthetic Maintenance -Hurdles and Shortcomings

Esthetic anterior space maintenance.

This paper describes an appliance to replace prematurely lost maxillary anterior teeth. A review of the literature is given. The prosthesis is different from previous appliances in its use of intraorally placed composite-filled celluloid crown forms. This allows for superior control of both esthetics and functional occlusal relationships. A case presentation is given describing laboratory and o...

The hurdles of warfarin and the hurdles of clinical practice.

The Hurdles of Warfarin and the Hurdles of Clinical Practice To the Editor: We have carefully read the interesting article by Hylek et al focusing on a pivotal issue in the prevention of atrial fibrillation– related stroke.1 The article explored the challenge of guidelines adherence in an elderly population with atrial fibrillation at variable hemorrhagic risk profile. Only 51% of the entire po...

Professionalism and commercialism in esthetic dentistry

Cancer epidemiology: shortcomings and possibilities.

The development of the concepts of initiators and promoters in carcinogenesis necessitates deliberations of evidence from human cancer epidemiology. Recent arguments in favor of mortality data as a more reliable indicator of trends in cancer incidence than morbidity data collected from cancer registries are disputed. Inconsistency in the use of data is pointed out. Comparisons of data from canc...

Shortcomings in risk projection.

-Gonadotrophins, oestradiol, androstenedione, testosterone and dehydroepiandrosterone sulphate (DHAS) were measured sequentially in 72 patients with advanced breast cancer receiving endocrine therapy of various types. Tamoxifen significantly reduced gonadotrophins but did not effect other hormones. Danazol also reduced gonadotrophins. Aminoglutethimide (AGT) reduced oestradiol and DHAS but had ...